US Patent Issued to Vybion on May 19 for "Single chain intrabodies that alter huntingtin mutant degradation" (California Inventors)

ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,612, issued on May 19, was assigned to Vybion Inc. (Monterey, Calif.).

"Single chain intrabodies that alter huntingtin mutant degradation" was invented by Lee Alan Henderson (Monterey, Calif.) and Irene Alexandra Amaro (Monterey, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods of use are provided for intrabodies that bind and alter the effects of poly-glutamate protein aggregation in poly-glutamate associated diseases, such as in Huntington's disease. Intrabodies are provided that prevent poly-glutamate aggregation, gene dysregulation, and negative effects of Huntington's disease."

The patent was filed on July 23, 2021...