ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,588, issued on March 17, was assigned to VOYAGER THERAPEUTICS INC. (Lexington, Mass.).

"AAV capsids with increased tropism to brain tissue" was invented by Mathieu E. Nonnenmacher (Boston), Jinzhao Hou (Lexington, Mass.), Wei Wang (Lexington, Mass.), Matthew Child (Ashland, Mass.) and Shaoyong Li (Hopkinton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to compositions, methods, and processes for the preparation, use, and/or formulation of adeno-associated virus capsid proteins, wherein the capsid proteins comprise targeting peptide inserts for enhanced tropism to a target tissue."

The patent was filed on Nov. 16, 202...