ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,544,396, issued on Feb. 10, was assigned to VOGENX (Durham, N.C.).
"Compositions and methods for treating metabolic disease" was invented by Wiliam Owen Wilkison (Raleigh, N.C.), Bentley Cheatham (Durham, N.C.), James Trinca Green (Raleigh, N.C.) and Yoshikazu Fujimori (Azumino, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention described herein relates to oral dosage form therapies for treating metabolic disorders using combinations of inhibitors of SGLT1 and SGLT2. In such dosage forms, SGLT1 is effective in the intestinal lumen, and is either not absorbed, or poorly absorbed, while the SGLT2 inhibitor inhibits sugar reabsorption in th...