ALEXANDRIA, Va., June 2 -- United States Patent no. 12,642,840, issued on June 2, was assigned to Visterra Inc. (Waltham, Mass.) and The Children's Hospital of Philadelphia (Philadelphia).

"Methods of using interleukin-2 agents" was invented by Gregory Babcock (Marlborough, Mass.) and Wayne Hancock (Philadelphia).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides, among other things, methods of using IL-2 fusion proteins, comprising an IL-2 variant and an Pc region, to treat and/or prevent heart transplant rejections. Methods of treating heart disease or a symptom thereof, conditioning a subject for heart transplant, modulating immunosuppression, and selectively increasing regulator...