ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,237, issued on April 7, was assigned to Viramal Ltd. (London).

"Mucoadhesive gel composition" was invented by William Bologna (New York), Francois Boutignon (Clermont-Ferrand, France), Lea Louvel (Villons-les-Buissons, France), Finn Larsen (Hawick, Great Britain), Simona Fiore (London) and Oliver Bates (London).

According to the abstract* released by the U.S. Patent & Trademark Office: "A pharmaceutical mucoadhesive gel composition for delivering therapeutic agents (such as progesterone) by buccal, nasal, vaginal and rectal administration, thereby avoiding the hepatic first-pass metabolism. The gel composition comprises a vehicle with a gel-forming agent and a bioadhesive agent; ...