ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,715,864, issued on Aug. 25, was assigned to VICORE PHARMA AB (Stockholm).

"Process for the synthesis of N-butyloxycarbonyl-3-(4-imidazol-1-ylmethylphenyl)-5-iso-butylthiophene-2-sulfonamide" was invented by Dmitrijs Cernaks (Pinki, Latvia) and Eliza Dege (Pinki, Latvia).

According to the abstract* released by the U.S. Patent & Trademark Office: "There is provided a new process for the synthesis of compounds of formula I, which are useful as angiotensin (Ang II) type 2 receptor agonists: by reacting a compound of formula II, with an excess of a compound of formula III, wherein W, Z and X have meanings given in the description; followed by reaction of the intermediate so formed with a ...