US Patent Issued to Vertex Pharmaceuticals on July 7 for "Processes for preparing modulators of alpha-1 antitrypsin" (Massachusetts Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,673,952, issued on July 7, was assigned to Vertex Pharmaceuticals Inc. (Boston).

"Processes for preparing modulators of alpha-1 antitrypsin" was invented by Cavan McKeon Bligh (Melrose, Mass.), Robert Daniel Giacometti (Malden, Mass.), Cristian Harrison (Beverly, Mass.), Stephen W. Laws (Dorchester, Mass.), Adam Looker (Newtonville, Mass.) and Stefanie Roeper (Medford, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides large-scale processes for preparing a modulator of alpha-1 antitrypsin (AAT) activity that may be useful for treating alpha-1 antitrypsin deficiency (AATD), such as 4-(5-(4-fluorophenyl)-6-(tetrahydro-2H-pyran-4-...