US Patent Issued to Versiti Blood Research Institute Foundation on Jan. 13 for "BCG car constructs and methods of their manufacture and use" (Wisconsin Inventor)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,651, issued on Jan. 13, was assigned to Versiti Blood Research Institute Foundation Inc. (Milwaukee).

"BCG car constructs and methods of their manufacture and use" was invented by Weiguo Cui (Brookfield, Wis.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are antibodies and antigen binding fragments thereof specific to BCG antigen Ag85B as well as chimeric antigen receptors and lymphocytes comprising Ag85B antibodies as described and methods of treating cancer and tuberculosis infections using the CAR lymphocytes described. In a first aspect, provided herein is an isolated antibody or antigen binding fragment thereof capable of bindi...