ALEXANDRIA, Va., April 7 -- United States Patent no. 12,597,137, issued on April 7, was assigned to Ventana Medical Systems Inc. (Tucson, Ariz.).

"Digital synthesis of histological stains using multiplexed immunofluorescence imaging" was invented by Xingwei Wang (Sunnyvale, Calif.), Zuo Zhao (Palo Alto, Calif.), Auranuch Lorsakul (Santa Clara, Calif.) and Yao Nie (Sunnyvale, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Techniques for obtaining a synthetic histochemically stained image from a multiplexed immunofluorescence (MPX) image may include producing an N-channel input image that is based on information from each of M channels of an MPX image of a tissue section, where M and N are positive inte...