ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,464, issued on Sept. 9, was assigned to VedaBio Inc. (San Diego).
"Detection assays" was invented by Ashish Pandey (San Diego), Anurup Ganguli (San Diego), Ariana Mostafa (San Diego) and Jacob Berger (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "Presented is a nucleic acid-guided nuclease cascade assay that can detect one or more target nucleic acids of interest of interest without the need for amplifying the target nucleic acids of interest. The nucleic acid-guided nuclease cascade assays utilize signal amplification mechanisms comprising various components including nucleic acid-guided nucleases and guide RNAs (gRNAs) forming ribonucl...