ALEXANDRIA, Va., Feb. 17 -- United States Patent no. 12,553,038, issued on Feb. 17, was assigned to VedaBio Inc. (San Diego).

"Delivery of therapeutics in vivo via a crispr-based cascade system" was invented by Joshua Miller (San Diego), Andrew Garst (San Diego), Robert Plasschaert (San Diego), Swetha Murali (San Diego) and Anurup Ganguli (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to compositions of matter and methods used to activate effector nucleic acids and effector targets in vivo via a CRISPR-based cascade system. The compositions and methods achieve non-specific delivery of cascade system components to cells yet the cascade system works in a cell-specific ...