ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,273, issued on Nov. 3, was assigned to VANDERBILT UNIVERSITY (Nashville, Tenn.).
"PCR detection of small fragments of a known nucleic acid target" was invented by Frederick R. Haselton (Nashville, Tenn.) and Emily C. Kight (Nashville, Tenn.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure is directed to methods of detecting small fragments of known nucleic acid biomarkers. The method permits small fragment detection using a method that reconstructs a full-length amplicon from DNA fragments. The method includes use of a capture template oligonucleotide that contains part of a known biomarker amplicon sequence. When DNA amplicon fr...