US Patent Issued to Vanderbilt University on March 17 for "WDR5 inhibitors and modulators" (Tennessee, Maryland Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,227, issued on March 17, was assigned to Vanderbilt University (Nashville, Tenn.).

"WDR5 inhibitors and modulators" was invented by Taekyu Lee (Brentwood, Tenn.), Changho Han (Nashville, Tenn.), Jonathan J. Mills (Nashville, Tenn.), Kevin B. Teuscher (Nashville, Tenn.), Jianhua Tian (Montgomery, Md.), Kenneth M. Meyers (Nashville, Tenn.), Somenath Chowdhury (Nashville, Tenn.) and Stephen W. Fesik (Nashville, Tenn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Quinazolin-4(3H)-one, 2,3-dihydroquinazolin-4(1H)-one, 3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one, and 3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione compounds and derivatives inhibit WDR5 a...