ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,508,233, issued on Dec. 30, was assigned to Vanderbilt University (Nashville, Tenn.).
"Graft copolymers, methods of forming graft copolymers, and methods of use thereof" was invented by John T. Wilson (Nashville, Tenn.), Daniel Shae (Nashville, Tenn.) and Dinh Chuong Nguyen (Ho Chi Minh, Viet Nam).
According to the abstract* released by the U.S. Patent & Trademark Office: "A graft copolymer and a method of delivering an active agent to a subject are provided. The graft copolymer includes a polymer backbone, a hydrophilic segment grafted to the polymer backbone, a pH-responsive segment grafted to the polymer backbone, and an endosomal disruption segment grafted to the polymer backbone...