US Patent Issued to Vanderbilt University on April 14 for "Antagonists of the muscarinic acetylcholine receptor M4" (Tennessee Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,726, issued on April 14, was assigned to Vanderbilt University (Nashville, Tenn.).

"Antagonists of the muscarinic acetylcholine receptor M4" was invented by Craig W. Lindsley (Brentwood, Tenn.), Thomas M. Bridges (Nashville, Tenn.), P. Jeffrey Conn (Nashville, Tenn.), Aaron M. Bender (Spring Hill, Tenn.) and Darren W. Engers (Brentwood, Tenn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are cyclopropylpiperidine compounds, which may be useful as antagonists of the muscarinic acetylcholine receptor M4 (niAChR M4). Also disclosed herein are methods of making the compounds, pharmaceutical compositions comprising the compounds, and m...