US Patent Issued to USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I., UNIVERZITA KARLOVA on Aug. 18 for "Selective ligands of human constitutive androstane receptor" (Czech Inventors)

ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,619, issued on Aug. 18, was assigned to USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (Prague) and UNIVERZITA KARLOVA (Prague).

"Selective ligands of human constitutive androstane receptor" was invented by Radim Nencka (Roztoky, Czech Republic), Ivana Mejdrova (Prague), Petr Pavek (Hradec Kralove, Czech Republic) and Jan Dusek (Prelouc, Czech Republic).

According to the abstract* released by the U.S. Patent & Trademark Office: "A structurally novel class of heterocyclic compounds of general formula I wherein L1 is heteroaryl and L2 is heteroaryl or aryl is disclosed. The novel compounds are useful in a method of prevention or treatment of a condition that is mediated by the ac...