US Patent Issued to University of Virginia Patent Foundation on Feb. 10 for "Compositions and methods for making and using bispecific antibodies" (Virginia Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,739, issued on Feb. 10, was assigned to University of Virginia Patent Foundation (Charlottesville, Va.).

"Compositions and methods for making and using bispecific antibodies" was invented by Jogender Tushir-Singh (Free Union, Va.) and Sanchita Bhatnagar (Free Union, Va.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A bispecific antibody that includes a first antigen binding site that is specific for a death receptor 5 (DR5) polypeptide and a second antigen binding site that is specific for a folate receptor alpha-1 (FOLR1) polypeptide, wherein the bispecific antibody includes: (i) a heavy chain amino acid sequence that includes SEQ ID NO:1 and a li...