US Patent Issued to University of Virginia Patent Foundation, Tufts Medical Center on Sept. 29 for "Compositions and methods for treating age-related macular degeneration" (Virginia, Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,746,246, issued on Sept. 29, was assigned to University of Virginia Patent Foundation (Charlottesville, Va.) and Tufts Medical Center Inc. (Boston).

"Compositions and methods for treating age-related macular degeneration" was invented by Paul Andrew Yates (Charlottesville, Va.), Elias Reichel (Weston, Mass.) and Ashton Leone (Charlottesville, Va.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are chemically modified tetracycline (CMT) derivatives for the treatment of non-exudative macular degeneration. The CMT derivatives lack antimicrobial activity, include a phenol ring, and a chemical structure sufficient to chelate Zn2+. Methods of inhibit...