ALEXANDRIA, Va., July 21 -- United States Patent no. 12,686,701, issued on July 21, was assigned to University of Vermont and State Agricultural College (Burlington, Vt.).

"Substitution of histidine with 2-thiohistidine in bioactive peptides" was invented by Robert J. Hondal (Burlington, Vt.) and Kaelyn Jenny (Essex Junction, Vt.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Presented is a method to incorporate 2-thiohistidine (2-thioHis) into a peptide. Also provided are peptides incorporating 2-thioHis, compositions, and methods of using the peptides incorporating 2-thioHis. The methods may be methods for scavenging metals and/or radicals or reducing oxidative stress. 2-thioHis has the following structure...