ALEXANDRIA, Va., May 12 -- United States Patent no. 12,625,149, issued on May 12, was assigned to University of Utah Research Foundation (Salt Lake City).
"Pathologic TDP-43 as a biomarker for the diagnosis of TDP-43 proteinopathy" was invented by Qinwen Mao (Salt Lake City).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are antibodies or antigen-binding fragments thereof and compositions comprising the same. Also disclosed are methods of detecting TAR DNA-binding protein 43 (TDP-43) in a biological sample, diagnosing a neurodegenerative disease in a subject, and selecting whether to enroll a subject in a clinical trial for frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) u...