ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,714,757, issued on Aug. 25, was assigned to University of Utah Research Foundation (Salt Lake City) and University Of Flordia Research Foundation (Gainesville, Fla.).

"Methods and compositions for the expression of constitutively active RAP1A from a VMD2 promoter" was invented by Mary Elizabeth Hartnett (Salt Lake City), Haibo Wang (Salt Lake City), William Hauswirth (Knoxville, Tenn.) and Vince Chiodo (Gainesville, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are nucleic acid constructs comprising a nucleic acid sequence encoding a vitelliform macular dystrophy-2 (VMD2) promoter operably linked to a nucleic acid sequence encoding Rap1a...