US Patent Issued to University of Southern California on Feb. 24 for "FGFR inhibitors and uses thereof" (California Inventors)

ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,559,470, issued on Feb. 24, was assigned to University of Southern California (Los Angeles).

"FGFR inhibitors and uses thereof" was invented by Chao Zhang (Los Angeles), Renata Rezende Miranda (Los Angeles), Feng Ni (Los Angeles) and John Carpten (Los Angeles).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides novel FGFR inhibitors based on the pyridinylpyrimidine. The invention includes inhibitors with broad inhibitory activity against all FGFR isoforms, and inhibitors with selective inhibition against FGFR4. These novel pyridinylpyrimidine-based FGFR inhibitors, or their derivatives, have strong potential to be used to treat cancer."...