US Patent Issued to University of South Florida on Sept. 15 for "Modified UBE3A gene for a gene therapy approach for Angelman syndrome" (Florida, New York Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,734,250, issued on Sept. 15, was assigned to University of South Florida (Tampa, Fla.).

"Modified UBE3A gene for a gene therapy approach for Angelman syndrome" was invented by Kevin Ron Nash (Seffner, Fla.), Edwin John Weeber (Apollo Beach, Fla.) and Jennifer Leigh Daily (New York).

According to the abstract* released by the U.S. Patent & Trademark Office: "Angelman Syndrome (AS) is a genetic disorder occurring in approximately one in every 15,000 births. It is characterized by severe mental retardation, seizures, difficulty speaking and ataxia. The gene responsible for AS was discovered to be UBE3A and encodes for E6-AP, a ubiquitin ligase. A unique feature of this gene is that it ...