ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,543,712, issued on Feb. 10, was assigned to UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh).

"Genetically modified mouse with a disruption in an AANAT gene" was invented by Diane L. Carlisle (Pittsburgh), Robert Max Friedlander (Pittsburgh), Abhishek Jauhari (Pittsburgh) and Sergei Victorovich Baranov (Pittsburgh).

According to the abstract* released by the U.S. Patent & Trademark Office: "This document relates to non-human animal models (e.g., non-human mammalian models such as mouse models) for aging (e.g., neural aging). For example, non-human animal models having reduced or eliminated levels of aralkylamine N-acetyltransferase (AANAT) polypept...