US Patent Issued to UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, THE TEXAS A&M UNIVERSITY SYSTEM on April 14 for "Therapeutic small molecules for treatment of pulmonary hypertension" (Pennsylvania, Texas Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,599,592, issued on April 14, was assigned to UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh) and THE TEXAS A&M UNIVERSITY SYSTEM (College Station, Texas).

"Therapeutic small molecules for treatment of pulmonary hypertension" was invented by Stephen Yu-Wah Chan (Pittsburgh) and Seungchan Kim (Cypress, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are pathogenic mechanisms in pulmonary hypertension and molecular inhibitors of the same. Particularly, GSTP1 (glutathione S-transferase P1) have been demonstrated as having a role in regulating the endothelial ISCU function in pulmonary hypertension. Accord...