US Patent Issued to UNIVERSITY OF MASSACHUSETTS on Oct. 27 for "Identifying non-productive splice sites" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,467, issued on Oct. 27, was assigned to UNIVERSITY OF MASSACHUSETTS (Westborough, Mass.).

"Identifying non-productive splice sites" was invented by Athma A. Pai (Cambridge, Mass.), Jonathan K. Watts (Worcester, Mass.), Kaitlyn Brokaw (Worcester, Mass.), Eraj Shafiq Khokhar (Worcester, Mass.) and Zachary Kartje (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides methods of identifying non-productive splice sites in target RNA transcripts and antisense oligonucleotides that increase the expression of said target RNA transcripts. In an embodiment, the target RNA transcript comprises ADAR, ARSA, ATPIA2, CACNA...