US Patent Issued to UNIVERSITY OF MASSACHUSETTS on Nov. 3 for "Modified guide RNAS for CRISPR genome editing" (Massachusetts Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,219, issued on Nov. 3, was assigned to UNIVERSITY OF MASSACHUSETTS (Westborough, Mass.).

"Modified guide RNAS for CRISPR genome editing" was invented by Erik Joseph Sontheimer (Auburndale, Mass.), Anastasia Khvorova (Westborough, Mass.), Jonathan Kenneth Watts (Worcester, Mass.), Aamir Mir (Worcester, Mass.), Julia Frances Alterman (Worcester, Mass.), Matthew Ryan Hassler (Worcester, Mass.), Michael Harry Brodsky (Sudbury, Mass.) and Alexandre Jean-Marie Debacker (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Chemically modified crRNAs and tracrRNAs are provided. crRNAs and tracrRNAs with 5' and/or 3' conjugated moieties are provide...