US Patent Issued to UNIVERSITY OF MASSACHUSETTS on March 17 for "Programmable DNA base editing by Nme2Cas9-deaminase fusion proteins" (Massachusetts, California Inventors)

ALEXANDRIA, Va., March 17 -- United States Patent no. 12,577,546, issued on March 17, was assigned to UNIVERSITY OF MASSACHUSETTS (Westborough, Mass.).

"Programmable DNA base editing by Nme2Cas9-deaminase fusion proteins" was invented by Erik J Sontheimer (Auburndale, Mass.), Xin Gao (Maynard, Mass.), Aamir Mir (Pleasanton, Calif.), Alireza Edraki (Worcester, Mass.), Scot A Wolfe (Winchester, Mass.) and Pengpeng Liu (Worcester, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is related to the field of gene editing. In particular, the gene editing is directed toward single nucleotide base editing. For example, such single nucleotide base editing results in a conversion of a OG base ...