ALEXANDRIA, Va., March 24 -- United States Patent no. 12,582,710, issued on March 24, was assigned to UNIVERSITY OF HOUSTON SYSTEM (Houston).

"Single-chain coronavirus viral membrane protein complexes" was invented by Ke-He Ruan (Bellaire, Texas), Xinli Liu (Sugar Land, Texas) and Renzhong Lu (Houston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Recombinant protein coronavirus antigens and vaccine compositions using the same, include a recombinant protein that is a single-chain (SC) viral membrane protein complex derived from the spike (S), envelop (E) and membrane (M) protein of a coronaviruses such as SARS-CoV-2, the causal agent for COVID-19. Methods for immunization of a subject using the vaccine compo...