US Patent Issued to University of Florida Research Foundation on Oct. 27 for "Methods of tolerizing a subject to a viral vector" (Florida Inventors)

ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,773,451, issued on Oct. 27, was assigned to University of Florida Research Foundation Inc. (Gainesville, Fla.).

"Methods of tolerizing a subject to a viral vector" was invented by Barry John Byrne (Gainesville, Fla.) and Manuela Corti (Alachua, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described are viral vectors, compositions, kits, and methods or using the vectors, compositions, kits to modulate immune response in a subject. The viral vectors include therapeutic recombinant adeno-associated viruses (rAAVs) and tolerance inducing rAAVs. The therapeutic rAAVs and tolerance inducing AAVs can be used to deliver one or more therapeutic nucleic ac...