US Patent Issued to University of Florida Research Foundation on Feb. 24 for "Compositions for treatment of diffuse intrinsic pontine glioma" (Florida Inventors)

ALEXANDRIA, Va., Feb. 24 -- United States Patent no. 12,558,407, issued on Feb. 24, was assigned to University of Florida Research Foundation Inc. (Gainesville, Fla.).

"Compositions for treatment of diffuse intrinsic pontine glioma" was invented by Elias Sayour (Newberry, Fla.), James Andrew McGuiness (Gainesville, Fla.), Hector Ruben Mendez-Gomez (Gainesville, Fla.) and Duane A. Mitchell (Gainesville, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compositions comprising a liposome comprising RNA molecules and a cationic lipid, wherein the RNA molecules encode at least one MHC Class II epitope of a mutant Histone 3 (H3) protein comprising a K27M mutation and optionally at least one ...