ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,729,209, issued on Sept. 8, was assigned to University of Florida Research Foundation Inc. (Gainesville, Fla.) and Smithsonian Institution (Washington).

"Macrocyclic compounds and methods of treatment" was invented by Hendrik Luesch (Gainesville, Fla.), Valerie J. Paul (Fort Pierce, Fla.), Susan Matthew (Gainesville, Fla.), Qi-Yin Chen (Gainesville, Fla.) and Ranjala Ratnayake (Gainesville, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The instant invention describes macrocyclic compounds having antiproliferation activity, and methods of treating disorders such as cancer, tumors and cell proliferation related disorders."

The patent was filed on O...