US Patent Issued to University Health Network, Sinai Health System on June 9 for "Methods of capturing cell-free methylated DNA and uses of same" (Canadian Inventors)

ALEXANDRIA, Va., June 9 -- United States Patent no. 12,649,915, issued on June 9, was assigned to University Health Network (Toronto) and Sinai Health System (Toronto).

"Methods of capturing cell-free methylated DNA and uses of same" was invented by Daniel Diniz De Carvalho (Toronto), Shu Yi Shen (Markham, Canada) and Rajat Singhania (Toronto).

According to the abstract* released by the U.S. Patent & Trademark Office: "There is described herein, a method of capturing cell-free methylated DNA from a sample having less than 100 mg of cell-free DNA, comprising the steps of: subjecting the sample to library preparation to permit subsequent sequencing of the cell-free methylated DNA; adding a first amount of filler DNA to the sample, wherein a...