US Patent Issued to UNIVERSITAT STUTTGART on Sept. 15 for "TNFR2 agonists with improved stability" (German Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,472, issued on Sept. 15, was assigned to UNIVERSITAT STUTTGART (Stuttgart, Germany).

"TNFR2 agonists with improved stability" was invented by Roman Fischer (Nuremberg, Germany), Martin Siegemund (Stuttgart, Germany), Klaus Pfizenmaier (Tiefenbronn, Germany) and Roland Kontermann (Nurtingen, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to polypeptide consisting of three TNF homology domains of TNF-ligand family members proteins (THD) that specifically bind to the extracellular part of TNFR2, wherein C-terminal and N-terminal reference points are defined by consensus sequences. The THDs are linked by short stre...