ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,735,420, issued on Sept. 15, was assigned to Universitaetsklinikum Tuebingen (Tuebingen, Germany).

"Imidazo[4,5-cquinoline compounds and their use as ATM kinase inhibitors" was invented by Stefan Laufer (Heidelberg, Germany), Michael Forster (Heidelberg, Germany), Teodor Dimitrov (Heidelberg, Germany), Lars Zender (Heidelberg, Germany) and Athina Moschopoulou (Heidelberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to imidazo[4,5-c]quinoline compounds and to their use in the inhibition, regulation and/or modulation of signal transduction by ATM kinase and, in particular, for the treatment of ATM mediated disease...