US Patent Issued to UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA, Fondazione Per La Ricerca Sulla Fibrosi Cistica, Istituto Giannina Gaslini on March 24 for "Use of esculentin and its derivatives for use in the treatment of cystic fibrosis" (Italian Inventors)

ALEXANDRIA, Va., March 24 -- United States Patent no. 12,583,893, issued on March 24, was assigned to UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA (Rome), Fondazione Per La Ricerca Sulla Fibrosi Cistica (Verona, Italy) and Istituto Giannina Gaslini (Genoa, Italy).

"Use of esculentin and its derivatives for use in the treatment of cystic fibrosis" was invented by Maria Luisa Mangoni (Rome) and Loretta Ferrera (Genoa, Italy).

According to the abstract* released by the U.S. Patent & Trademark Office: "Are disclosed pharmaceutical compositions comprising as active ingredients Esculentin-1a(1-21)NH2 and/or Esculentin diastereomer Esc(1-21)-1c for use for restoring dysregulation of water and/or ions content and/or composition of the periciliary l...