US Patent Issued to uniQure IP on Nov. 3 for "RNAi induced Huntingtin gene suppression" (Dutch Inventors)

ALEXANDRIA, Va., Nov. 3 -- United States Patent no. 12,781,223, issued on Nov. 3, was assigned to uniQure IP B.V. (Amsterdam).

"RNAi induced Huntingtin gene suppression" was invented by Pavlina Stefanova Konstantinova (Amsterdam) and Jana Minarikova (Amsterdam).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides for a double stranded RNA comprising a first RNA sequence and a second RNA sequence wherein the first and second RNA sequence are substantially complementary, wherein the first RNA sequence has a sequence length of at least 19 nucleotides and is substantially complementary to SEQ ID NO. 1. Said double stranded RNA is for use in inducing RNAi against Huntingtin exon 1 sequence...