ALEXANDRIA, Va., July 15 -- United States Patent no. 12,662,455, issued on June 23, was assigned to UCB Biopharma SRL (Brussels).

"Tetrahydrobenzo-quinoline sulfonamide derivatives useful as IgE modulators" was invented by Timothy John Norman (Slough, Great Britain), Selvaratnam Suganthan (Abingdon, Great Britain), Jag Paul Heer (Slough, Great Britain) and Zeshan Yousuf (Abingdon, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to tetrahydrobenzo-isoquinoline sulfonamide derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast...