US Patent Issued to TRUSTEES OF DARTMOUTH COLLEGE on Oct. 6 for "Androgen receptor modulators" (Vermont Inventor)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,202, issued on Oct. 6, was assigned to TRUSTEES OF DARTMOUTH COLLEGE (Hanover, N.H.).

"Androgen receptor modulators" was invented by Glenn C. Micalizio (Norwich, Vt.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to polycyclic (e.g., tetracyclic) androgen receptor (AR) modulators, synthetic methods for preparing such AR modulators, and methods of using such AR modulators to treat an androgen-dependent condition, such as prostate cancer or BPH. Exemplary compounds have quaternary centers at C9 and C13 in which the quaternary center at C9 projects a substituent on the opposite face of the tetracycle as the substituent at ...