ALEXANDRIA, Va., March 17 -- United States Patent no. 12,578,274, issued on March 17, was assigned to Trustees of Dartmouth College (Hanover, N.H.).

"Label-free, on-chip detection of opioids through surface-enhanced raman spectroscopy" was invented by Michael Zhang (Hanover, N.H.), Congran Jin (White River Junction, Vt.), Yuan Nie (Hanover, N.H.), Yundong Ren (Lebanon, N.H.), Nanjing Hao (Hanover, N.H.) and John X. J. Zhang (Hanover, N.H.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Opioids can be detected using a test system with ZnO pillars arranged in an array on a silicon wafer. Silver particles are on a top surface and/or side surface of the ZnO pillars. A sample fluid is applied to the test system. A...