US Patent Issued to Trustees of Boston University on July 7 for "Aptamer and ribozyme equilibrium shifting (ARES) RNA circuits and uses thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., July 7 -- United States Patent no. 12,674,171, issued on July 7, was assigned to Trustees of Boston University (Boston).

"Aptamer and ribozyme equilibrium shifting (ARES) RNA circuits and uses thereof" was invented by Alexander Arthur Green (Chestnut Hill, Mass.) and McKayla Taylor Masity (Brighton, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The technology described herein is directed to Aptamer and Ribozyme Equilibrium Shifting (ARES) regions, including ON-switches and OFF-switches, which can be harnessed to regulate the stability of RNA molecules. Also described herein are compositions comprising such RNA molecules and methods of using them to regulate translation of cargo polype...