US Patent Issued to Trustees of Boston University on Aug. 18 for "Regulated synthetic gene activation systems" (Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,637, issued on Aug. 18, was assigned to Trustees of Boston University (Boston).

"Regulated synthetic gene activation systems" was invented by Ahmad S. Khalil (Lexington, Mass.), Kok Ann Gan (Allston, Mass.), Hanrong Ye (Brighton, Mass.) and Thea Samuelle Ornstein (Boston).

According to the abstract* released by the U.S. Patent & Trademark Office: "The technology described herein is directed to regulated synthetic gene expression systems. In one aspect described herein are synthetic transcription factors (synTFs) comprising a DNA binding domain, a transcriptional activator domain, a transcriptional effector domain (TED), and optionally a regulator protein. In other aspects describ...