ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,198, issued on Sept. 29, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"Phenolic acid lipid based cationic lipids" was invented by Shrirang Karve (Cambridge, Mass.), Frank DeRosa (Cambridge, Mass.), Apiwat Wangweerawong (Cambridge, Mass.) and Saswata Karmakar (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides, in part, phenolic acid lipid compounds of Formula (I), and sub-formulas thereof, or a pharmaceutically acceptable salt thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordi...