US Patent Issued to TRANSLATE BIO on Sept. 15 for "Processes of preparing mRNA-loaded lipid nanoparticles" (Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,734,253, issued on Sept. 15, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).

"Processes of preparing mRNA-loaded lipid nanoparticles" was invented by Shrirang Karve (Lexington, Mass.), Ashish Sarode (Lexington, Mass.) and Frank DeRosa (Lexington, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides an improved process for lipid nanoparticle formulation and mRNA encapsulation. In some embodiments, the present invention provides a process of encapsulating messenger RNA (mRNA) in lipid nanoparticles comprising a step of mixing a suspension of preformed lipid nanoparticles and mRNA."

The patent was filed on March 12, 20...