ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,645, issued on March 3, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"Methods for treatment of methylmalonic acidemia" was invented by Lianne Boeglin (Lexington, Mass.), Christian Cobaugh (Lexington, Mass.), Frank DeRosa (Lexington, Mass.), Michael Heartlein (Lexington, Mass.) and Kim Askew (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides, among other things, methods and compositions for treating methylmalonic academia (MMA) based on mRNA therapy. The compositions used in treatment of MMA comprise an mRNA comprising a methymalonyl-CoA mutase (MUT) coding sequence and are administered at an effec...