ALEXANDRIA, Va., Aug. 5 -- United States Patent no. 12,697,302, issued on Aug. 4, was assigned to Translate Bio Inc. (Waltham, Mass.).
"Tricine and citric acid lipids" was invented by Shrirang Karve (Lexington, Mass.) and Frank DeRosa (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are cationic lipids which are compounds of Formula (A). Cationic lipids provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins."
The patent was filed on June 19, 2020, un...