US Patent Issued to TMEM16A on Feb. 10 for "Pyridine derivatives as calcium-activated chloride channel modulators" (British Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,658, issued on Feb. 10, was assigned to TMEM16A Ltd. (Welwyn Garden City, Great Britain).

"Pyridine derivatives as calcium-activated chloride channel modulators" was invented by Stephen Collingwood (Brighton, Great Britain), Craig Buxton (Abingdon, Great Britain), Matthew Habgood (Abingdon, Great Britain), Jonathan David Hargrave (Abingdon, Great Britain), Thomas Beauregard Schofield (Abingdon, Great Britain), Matthew Smith (Abingdon, Great Britain) and Christopher Stimson (Abingdon, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compounds of general formula (I), wherein R1, R2, R3, R4, R5, X1, X2 and X3 are as defined herein are usefu...