ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,410, issued on Oct. 6, was assigned to TIANJIN MEDICAL UNIVERSITY (Tianjin, China).
"FATS as a target for treating tumors and uses thereof" was invented by Rongxin Zhang (Tianjin, China), Kai Zhang (Tianjin, China), Lijuan Zhang (Tianjin, China), Zhenyi Xue (Tianjin, China) and Yan Li (Tianjin, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "A composition including modified macrophages and its use in the treatment of melanoma and pancreatic cancer. The modified macrophages have a deletion of fragile-site associated tumor suppressor (FATS) or include a small interfering RNA (siRNA) capable of silencing the FATS. The knockout or inhibition of FATS...