ALEXANDRIA, Va., Sept. 15 -- United States Patent no. 12,733,810, issued on Sept. 15, was assigned to THORNHILL SCIENTIFIC INC. (North York, Canada).

"Dynamic susceptibility contrast using a pre-determined arterial input function" was invented by James Duffin (Toronto), Joseph Arnold Fisher (Thornhill, Canada), David Mikulis (Oakville, Canada), Ece Su Sayin (Windsor, Canada), Jacob B. Schulman (Toronto), Olivia Sobczyk (Etobicoke, Canada) and Kamil Uludag (Toronto).

According to the abstract* released by the U.S. Patent & Trademark Office: "Hypoxia-induced deoxyhemoglobin concentration ([dOHb]) may be used as a susceptibility contrast agent in subjects. With sequential gas delivery methods, reoxygenation can be implemented abruptly, induc...