ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,604, issued on Dec. 16, was assigned to Theripion Inc. (Shoreline, Wash.).
"RNase-PON1 fusion polypeptides and related compositions and methods" was invented by Jeffrey A. Ledbetter (Shoreline, Wash.) and Martha S. Hayden-Ledbetter (Shoreline, Wash.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods relating to paraoxonase fusion polypeptides are disclosed. In some aspects, the fusions are bispecific molecules that include a first biologically active polypeptide linked amino-terminal to a biologically active paraoxonase, wherein the first biologically active polypeptide is a DNase, an RNase, a SOD1, a CTLA-4 extracellular domain...